Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes. but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown. Methods: We used a modified Delphi approach to identify safety criteria for an opt-out protocol to guide de-escalation or discontinuation of antibiotic... https://www.scrapajul.com/product-category/womens-footwear/